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Factory Sells Best Quality 2-CHLORO-N-ETHYLACETAMIDE 105-35-1 with stock
- Molecular Formula: C4H8 Cl N O
- Molecular Weight: 121.567
- Vapor Pressure: 0.0159mmHg at 25°C
- Melting Point: 129 °C(Solv: benzene (71-43-2))
- Boiling Point: 255.9 °C at 760 mmHg
- PKA: 14.39±0.46(Predicted)
- Flash Point: 108.6 °C
- PSA： 29.10000
- Density: 1.086 g/cm3
- LogP: 0.75220
2-CHLORO-N-ETHYLACETAMIDE(Cas 105-35-1) Usage
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General Description |
2-Chloro-N-ethylacetamide is a chemical compound with the molecular formula C4H8ClNO. It is also known by its IUPAC name, Ethyl 2-chloroacetamide. It is used in the synthesis of a variety of chemical products and is a useful tool in molecular chemistry. As the name indicates, this compound contains a chlorine atom and an ethyl group bound to an acetamide functional group, resulting in unique reactions under certain conditions. Like many chemicals, it should be handled carefully due to potential health risks and environmental impact. |
InChI:InChI=1/C4H8ClNO/c1-2-6-4(7)3-5/h2-3H2,1H3,(H,6,7)
105-35-1 Relevant articles
Rational Design, Synthesis, and Biological Activity of N-(1,4-Benzoxazinone)Acetamide Derivatives as Potent Platelet Aggregation Inhibitors
Xiang, Yi,Wang, Xiu-Hua,Yang, Quan,Tan, Jia-Lian,Jang, Hee-Jae,Zuo, Hua,Shin, Dong-Soo
, p. 146 - 155 (2018)
Inappropriate thrombus formation within ...
Effective Synthesis of 3,4-Diaryl-isoxazole-5-carboxamides and their Antiproliferative Properties
Maksimenko, Anna S.,Kislyi, Victor P.,Chernysheva, Natalia B.,Strelenko, Yuri A.,Zubavichus, Yan V.,Khrustalev, Victor N.,Semenova, Marina N.,Semenov, Victor V.
, p. 4260 - 4270 (2019/07/12)
A simple scalable procedure for the synt...
Synthesis and acaricidal activities of scopoletin phenolic ether derivatives: Qsar, molecular docking study and in silico Adme predictions
Luo, Jinxiang,Lai, Ting,Guo, Tao,Chen, Fei,Zhang, Linli,Ding, Wei,Zhang, Yongqiang
, (2018/05/04)
Thirty phenolic ether derivatives of sco...
1,3-dimethyl-7-substituted-quinazolinyl-2,4-diones, and synthesis method and application thereof
-
Paragraph 0056; 0057; 0058; 0059; 0060; 0095; 0096, (2017/07/31)
The invention discloses 1,3-dimethyl-7-s...
105-35-1 Process route
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75-04-7,85404-22-4
ethylamine
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-
79-04-9
chloroacetyl chloride
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-
105-35-1
2-chloro-N-ethylacetamide
| Conditions | Yield |
|---|---|
|
With
benzene;
|
|
|
With
sodium hydroxide;
|
|
|
In
tetrahydrofuran;
at 5 ℃;
for 1h;
|
|
|
With
sodium hydroxide; ammonia;
In
1,2-dichloro-ethane;
at -15 - -10 ℃;
for 0.75h;
|
|
|
With
potassium carbonate;
In
dichloromethane;
at 20 ℃;
Cooling with ice;
|
|
|
With
triethylamine;
In
dichloromethane;
at 20 ℃;
|
|
|
With
potassium carbonate;
In
dichloromethane;
at 20 ℃;
Cooling with ice;
|
|
|
ethylamine;
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 0.0833333h;
chloroacetyl chloride;
In
dichloromethane;
at 0 - 20 ℃;
for 0.25h;
|
|
|
With
triethylamine;
In
acetonitrile;
at 20 ℃;
for 1h;
|
-
-
79-04-9
chloroacetyl chloride
-
-
105-35-1
2-chloro-N-ethylacetamide
| Conditions | Yield |
|---|---|
|
With
ethylamine;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 3.83h;
|
81%
|
105-35-1 Upstream products
-
4960-82-1
dichlorodiacetamide
-
75-04-7
ethylamine
-
79-04-9
chloroacetyl chloride
105-35-1 Downstream products
-
62029-79-2
2-amino-N-ethyl-acetamide
-
42275-79-6
Dichloroacetic acid ethylamide
-
14301-39-4
trichloro-acetic acid ethylamide
-
116-01-8
ethoate-methyl
