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(aminomethylene)bisphosphonic acid

  • CAS No.: 29712-28-5
  • Purity: 99%
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What is the (aminomethylene)bisphosphonic acid ?

(aminomethylene)bisphosphonic acid is , while it's Molecular Formula is CH7 N O6 P2. Used in Pharmaceutical Industry:
(Aminomethylene)bisphosphonic acid is used as a bone-preserving medication for the treatment of osteoporosis and Paget's disease of bone. It is utilized to inhibit bone resorption and increase bone density, which helps in reducing the risk of fractures and maintaining overall bone health.
Used in Orthopedics:
In the field of orthopedics, (aminomethylene)bisphosphonic acid is used as an adjunct therapy to support bone health and prevent bone loss in patients with various bone-related conditions. Its ability to inhibit bone breakdown and increase bone density makes it a valuable treatment option for improving bone strength and reducing the risk of fractures.
Used in Geriatrics:
(Aminomethylene)bisphosphonic acid is used as a preventive and therapeutic agent in geriatrics to address age-related bone loss and osteoporosis. By increasing bone density and reducing the risk of fractures, it helps in maintaining the mobility and independence of elderly patients.
Used in Oncology:
In oncology, (aminomethylene)bisphosphonic acid is used to manage bone metastases and reduce the risk of skeletal-related events in patients with cancer. Its bone-preserving properties help in improving the quality of life and overall prognosis of cancer patients with bone involvement.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of (aminomethylene)bisphonic acid, various drug delivery systems have been developed. These systems, including organic and metallic nanoparticles, serve as carriers for the drug, improving its delivery to target sites and therapeutic outcomes while minimizing side effects.

What is the CAS number for (aminomethylene)bisphosphonic acid ?

The CAS number of (aminomethylene)bisphosphonic acid is 29712-28-5.

More information of (aminomethylene)bisphosphonic acid 29712-28-5 are:

Synonyms

Phosphonicacid, (aminomethylene)bis- (9CI); Phosphonic acid, (aminomethylene)di- (8CI);(Aminomethylene)di[phosphonic acid]; Aminomethanebis[phosphonic acid];Aminomethanediphosphonic acid; Aminomethylenebis[phosphonic acid];Aminomethylenediphosphonate; Methaneaminediphosphonic acid; NSC 669693

CAS?Number

29712-28-5

Molecular Formula

CH7 N O6 P2

Molecular Weight

191.017

Density

2.185g/cm3

Melting Point

290-292 °C

Boiling Point

581.4°Cat760mmHg

Flash Point

305.4°C

HS CODE

2931900090

PSA

160.70000

LogP

-0.71560

Pka

0?+-.0.10(Predicted)

What is (aminomethylene)bisphosphonic acid (29712-28-5) used for?

(Aminomethylene)bisphosphonic acid, also known as alendronic acid, is a synthetic bisphosphonate drug primarily used to treat osteoporosis, Paget's disease, and other bone-related conditions. It functions by inhibiting bone breakdown and increasing bone density, thereby reducing the risk of fractures. As a synthetic analog of pyrophosphate, it is commonly prescribed in oral tablet form or administered intravenously for patients who cannot tolerate oral medication. While generally well-tolerated, it may cause gastrointestinal discomfort, musculoskeletal pain, and in rare cases, osteonecrosis of the jaw.

InChI:InChI=1/CH7NO6P2/c2-1(9(3,4)5)10(6,7)8/h1H,2H2,(H2,3,4,5)(H2,6,7,8)

Articles related to (aminomethylene)bisphosphonic acid:

Article

Source

Biologically active pyridine mono- and bis-phosphonates: Efficient ligands for co-ordination of Cu2+ ions

Boduszek, Bogdan,Dyba, Marcin,Jezowska-Bojczuk, Malgorzata,Kiss, Tamas,Kozlowski, Henryk

, p. 973 - 976 (1997)

Syntheses and evaluation of 68Ga- and 153Sm-labeled DOTA-conjugated bisphosphonate ligand for potential use in detection of skeletal metastases and management of pain arising from skeletal metastases

Chakraborty, Sudipta,Goswami, Dibakar,Chakravarty, Rubel,Mohammed, Sahiralam Khan,Sarma, Haladhar Deb,Dash, Ashutosh

, p. 1618 - 1626 (2018)

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