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Trimeprazine

  • CAS No.: 84-96-8
  • Purity: 99%
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What is the Trimeprazine ?

Trimeprazine is Light Yellow Solid, while it's Molecular Formula is C18H22 N2 S. Trimeprazine is used for treating itching during dermatitis of both allergic and nonallergic origin.

What is the CAS number for Trimeprazine ?

The CAS number of Trimeprazine is 84-96-8.

More information of Trimeprazine 84-96-8 are:

Synonyms

Phenothiazine,10-[3-(dimethylamino)-2-methylpropyl]- (6CI,8CI); (?à)-Alimemazine; (?à)-Trimeprazine; 10-(2-Methyl-3-dimethylaminopropyl)phenothiazine;10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine; Alimemazine; Alimezine;Bayer 1219; Methylpromazine; Teralen; Teralene; Trimeprazine; dl-Trimeprazine

CAS?Number

84-96-8

Molecular Formula

C18H22 N2 S

Molecular Weight

298.452

Density

1.203 g/cm3

Melting Point

68 ºC

Boiling Point

420.3°Cat760mmHg

Flash Point

208°C

PSA

31.78000

LogP

4.55200

Pka

pKa 9.00 (Uncertain)

What is Trimeprazine (84-96-8) used for?

Trimeprazine, also known as mepazine, is a first-generation antihistamine drug that belongs to the ethylenediamine class. It is characterized by its ability to block the H1 receptor, which is responsible for the allergic response. Trimeprazine exhibits antihistaminic, sedative, and weak anticholinergic properties, making it a versatile medication for various conditions.
Source:
Trimeprazine is synthesized chemically and is available in various pharmaceutical formulations, such as tablets, syrups, and injectable solutions.
Production Methods:
The synthesis of Trimeprazine involves the reaction of 2-(4-methylpiperazin-1-yl)ethanol with 2-chloro-N,N-dimethylethanamine to form the desired compound.

InChI:InChI=1/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3

Articles related to Trimeprazine:

Article

Source

Isobutazine specific impurity as well as analysis method and removal method thereof

-

Paragraph 0078-0079, (2021/05/01)

Endor Studies of Cation Radicals from Pharmacologically Active Phenothiazines

Helle, N.,Kurreck, H.,Bock, M.,Kieslich, W.

, p. 964 - 970 (2007/10/02)

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